PCR (Polymer Chain Reaction) upscales minute concentrations of polynucletides to detectable amounts. The fragments then are separated by electrophoresis with respect to chainlength.
Scanned frationation patterns are highly superresolvable, since the kernel is a somooth and perfectly reproducible parameter, especially with modern microtechniques.

The table describes the process of digital superresolution of PCR-data:

Step Black line: Original data
Grey solid: Superresolution
Green line: Kernel
Perform the separation and scan the pattern

Modern markers allow for exact mass-propotional detection of polynucleotide patterns, just like in classical HPLC.

Import of the scanned data into a resolver software is all, that's needed to achieve approximate duplicate resolution and removal of peak tails and asymmetries.


The example shows, how seemingly 8 peaks decompose into twelve ones.

Calculation time is less than 5 seconds and can be fully automatted.

Reducing sampling intervals,
High throughput optimization
Please consult the page 'Reducing sampling times in chromatography''

Superresolution requires robust baseline correction.
PROANALYSI::PEAKS, you find baseline-routines optimized especially for PCR.
The complete sequence of data analysis can be automatted and perfomed by simply pressing a button.